ABSTRACT
Extracts of 50 Egyptian higher plants were screened for their antibacterial activity by the agar diffusion technique. The extracts that exhibited the highest activities were further evaluated by measuring their minimum inhibitory concentrations [MIS]. Two organisms; namely, Staphylococcus aureus [ATCC 29523] and Escherichia coli [HP 101], were used
Subject(s)
Pharmacology , Plants, MedicinalABSTRACT
Extraction and fraction of the aerial parts of C. bruguierana afforded cnicin, 11,13-dehydromelitensin 8 alpha-acetate and the three 6-methoxyflavone derivatives cirsilineol, cirsimaritin and hispidulin 7-0-rutinoside. Identification of the isolated materials was established mainly by spectral as well as chemical methods
Subject(s)
Flavones/isolation & purificationABSTRACT
A cytotoxicity screening study was carried out on the ethanolic extracts of 50 unselected higher plants growing in Egypt. The assays were performed on 2 proliferating mouse cell lines, a normal fibroblast line [NIH3T3] and a virus-transformed [ras] line [KA31T]. 10% of the examined extracts exhibited substantial cytotoxic activity arbitrarily defined by LC50 of 10 mug/ml or less in both cell lines